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Download GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions Ebook Novel

GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions ebook

GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions Ebook

 By Annette Gilchrist

 Language: English

 Publish Year : 1970

 

Download GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions

 

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E-Book readable online or download on PDF DJVU TXT DOC MP3 CFM mobi and more formats for PC PDA MAC IPAD IPHONE Nook Kindle Android Tablets mobile phone and more devices. You can find AUDIO Books in mp3 formats



E-Book review:
"Additionally, the presentation of the fundamental concepts of GPCR biology by the authors, who are recognized experts in the GPCR field, is likely to be appreciated by students of pharmacology. . . This is a unique resource for navigating the field of GPCR research." (Doody's, 23 September 2011)

The fundamental guide on the basic concepts and medical significance of GPCRs

GPCR Molecular Pharmacology and Drug Targeting examines the complex inner workings of these proteins by balancing basic research concepts with practical aspects relevant to drug discovery. Throughout, it answers key questions surrounding research into GPCR function—how they get activated; how they signal across the cell membrane; how they couple to intracellular signaling partners; how they communicate to each other as well as to other receptors and other membrane proteins; and how their mutations lead to disease. At the same time, it explores the many ways in which the receptors can be screened at each of these critical steps for compounds that modulate their action. This book:

Provides vital information for scientists working to identify compounds that selectively target GPCRs

Presents detailed methods on how to express and manipulate GPCRs, as well as established and emerging methods to measure their activity

GPCR Molecular Pharmacology and Drug Targeting provides the historical groundwork and acts as an essential resource for any scientists working with this important and therapeutically relevant family. The in-depth discussions on recent findings and extensive coverage of screening approaches provide the necessary framework for encouraging exploration into malfunctioning GPCRs and identifying novel medicinal solutions.

 

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